The objectives of this study are to develop the total maximum daily loads simulation system, TOLOS that is capable of estimating annual nonpoint source pollution from small watersheds, to monitor the hydrology and water quality of the Balkan HP#6 watershed, and to validate TOLOS with the field data. TOLOS consists of three subsystems: the input data processor based on a geographic information system, the models, and the post processor. Land use pattern at the tested watershed was classified from the Landsat TM data using the artificial neutral network model that adopts an error back propagation algorithm. Paddy field components were added to SWAT model to simulate water balance at irrigated paddy blocks. SWAT model parameters were obtained from the GIS data base, and additional parameters calibrated with field data. TOLOS was then tested with ungauged conditions. The simulated runoff was reasonably good as compared with the observed data. And simulated water quality parameters appear to be reasonably comparable to the field data.