Static mixer consists of a straight pipe of circular cross section into which individual elements are inserted to cut, fold, twist and re-combine the mixing fluid. The number of elements and their shape required in any application depend on the complexity of the mixing process. The objectives of this study are to develop a new static mixer and to perform the experimental investigation of pressure drop in order to evaluate the performance of the new one. The mixing fluid used is Glycerin. The pressure drop is measured using a hydraulic manometer and the correlation of Z-factor is suggested as a function of Re. The Z-factors of SSC and YNU mixer are about 40% lower than and 4% higher than that of the Sulzer one.