Previously developed empirical equations used to calculate the parameters of the transient storage model are analyzed in depth in order to evaluate their behavior in representing solute transport in the natural streams with storage zone. A comparative analysis of the existing theoretical and experimental equations used to predict parameters of the transient storage (TS) model is reported. New simplified equations for predicting 4 key parameters of the TS model using hydraulic data sets that are easily obtained in the natural streams are also developed. The weighted one-step Huber method, which is one of the nonlinear multi-regression methods, is applied to derive new parameters equation. These equations are proven to be superior in explaining mixing characteristics of natural streams with the transient storage zone more precisely than the other existing equations.