This paper investigates how intentional mistuning of bladed disks reduces their sensitivity to unintentional random mistuning. The class of intentionally mistuned disks considered here is limited, for cost reasons, to arrangements of two types of blades (A and B, say). A two-step procedure is then described to optimize the arrangement of these blades around the disk to reduce the effects of unintentional random mistuning. First, a pure optimization effort is undertaken to obtain the pattern (s) of the A and B blades that yields small/the smallest value of the largest amplitude of response to a given excitation in the absence of unintentional random mistuning using Genetic Algorithm. Then, in the second step, a qualitative/quantitative estimate of the sensitivity for the optimized intentionally mistuned bladed disks with respect to unintentional random mistuning is performed by analyzing their amplification factor, probability density function and passband/stopband structures. Examples of application with simple bladed disk models demonstrate the significant benefits of using this class of intentionally mistuned disks.