With the recent trends of electronic commerce moving from B2C to B2B, Collaborative Product Commerce (CPC) is widely adopted as a part of B2B in the virtual collaborative environment. This paper proposes an integrated CPC framework supporting collaborative works between businesses by sharing product data and collaborative process between global enterprises and their customers, who are related to product life cycle, and integrating application systems in order to realize a true B2B electronic commerce. To integrate into a loosely coupled structure, various web service technologies such as XML, SOAP, WSDL and UDDI are utilized as its fundamentals and on that basis, a CPC integration framework is implemented through the Internet to support real-time operation providing interoperability among all the different applications operated on various platforms which have been developed using different languages and adopted by different companies.