In this paper, minimum mean-squared-error(MMSE) and blind equalization schemes were employed to improve bit-error-rate(BER) and to reduce inter-symbol interference(ISI) generated during storage and retrieval processes of two-dimensional data in a digital holographic data storage system. We explained methods for designing and applying MMSE and blind equalization to improve BER in a digital holographic data storage system. From experimental evaluations, we compared the BER performances of MMSE and blind equalization and we showed that the BER performances of MMSE and blind equalization were improved significantly compared with those before equalization.