In this paper, we proposed a method for acoustic echo cancellation based on independent component analysis. When the large acoustic noise is picked up by the microphone, the performance of echo cancellation decreased. We used two microphones that received echo signal which is linearly mixed with the noise, then separated the echo signals from the received signals with independent component analysis algorithm. The separated echo signal is used for the reference signal of adaptive algorithm which leads to better performance of the echo cancellation. Computer simulation results show the validity of the proposed method.