High-speed feed drive systems have been widely used in the manufacturing and semiconductor industries. Specifications for high-speed systems require more advanced capabilities than conventional feed drive systems. It is necessary to devise special design concepts to achieve the level of performance for high-speed feed drive systems. In this paper, an integrated design method is proposed for high-speed feed drive systems in which the interactions between mechanical and electrical subsystems ought to be considered simultaneously during the design process. Based on the integrated design method, a nonlinear optimal design procedure of mechanical subsystems considering the Abbe and radius errors is accomplished through the design process of electrical subsystems satisfying the control stability and the saturation condition of actuators as well as the relative stability. Both mechanical and electrical parameters are considered as design variables. Simulations and numerical case studies show that the integrated design method of high-speed feed drive systems creates results satisfying the desired performances of mechatronic systems.