The proposed simplified MDOF model is applied to a half-scale single-story reinforced masonry test building with a single diagonally-sheathed diaphragm. Comparisons of analytical studies to experimental tests can be valuable for understanding the seismic response of these types of buildings and for determining the qualities and limitations of the simplified models. A model calibration process is performed in this paper to determine the required structural properties based on the elastic and inelastic test responses for test building. This approach is necessary since established methods to determine the in-plane and out-of-plane stiffness, strength, and hysteresis do not exist.