Despite rapid technological advance and increased automation facilities, many jobs and activities in our living require manual materials handling(MMH). These include wide variety of activities such as moving things, lifting bags. boxes or cartons, etc. Many studies found that handle could affect on maximum acceptable weight of lifting, but there were few studies f3r the effects of work posture and coupling in lifting tote box. This study performed that ten male college students were required to lift a tote box with and without handle for three postures (bending, straight, right angle posture). From the experiment, following results were obtained. (1) MVC reduced maximum 23% by type of handle. (2) MVC was highest in straight posture, but was lowest in right angle posture. (3) As a result of ANOVA, MVC paid attention to posture and coupling. (p<0.01) (4) To all handle types, biceps brachii activity was increased in right angle posture. but reduced in straight posture. (5) To all posture, biceps brachii activity was most lively in no handle. The results of MVC measurement, subjective rating, EMG analysis, statistic analysis showed that maximum acceptable weight of lifting was influenced by type of handle and straight posture was more comfortable than other postures. Based on these results, it was concluded that acceptable weight of lifting has to differ for work posture and coupling.