To inject fresh air into a fire room, Positive Pressure Ventilation (PPV) can be used and the blower of PPV increases inside pressure of the room. It makes high flow rate of products of combustion, smoke and heat from the structure, and it is very helpful to fireman on the fire extinguishing work. The flame moves to the direction of airflow and the temperature of flame can be decreased rapidly. In this experiment, a water mist system is applied to PPV to increase the effectiveness, and various effective factors are studied. n-Heptane and pine wood stick were used as fuel. Temperatures at the above and behind the combustion pan were strongly reduced by the water mist system and by the convective cooling with airflow. The smoke density was also decreased by PPV with water mist system and it can be explained by the absorption of smoke particles on the water mist droplet and by the strong exhausting effects of mobile fan.