Synthesis of GlcNAcp- β-(1→3)-Galp- α-(1→2)-6-deoxy-altroHepp- α-(1→O-propyl, an O-Antigenic Repeating Unit from C. jejuni O:23 and O:36

Synthesis of GlcNAcp- β-(1→3)-Galp- α-(1→2)-6-deoxy-altroHepp- α-(1→O-propyl, an O-Antigenic Repeating Unit from C. jejuni O:23 and O:36

ㆍ 저자명: Yoon. Shin-Sook,Shin. Young-Sook,Chun. Keun-Ho,Nam Shin. Jeong E.
ㆍ 간행물명: Bulletin of the Korean Chemical Society
ㆍ 권/호정보: 2004년|25권 2호|pp.289-292 (4 pages)
ㆍ 발행정보: 대한화학회
ㆍ 파일정보: 정기간행물|
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ㆍ 주제분야: 기타

이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.

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기타언어초록

A trisaccharide, GlcNAcp- ${eta}-(1{ o}3)-Galp-{alpha}-(1{ o}2)$-6-deoxy-altroHepp- ${alpha}-(1{ o}O$-propyl, as an O-antigenic repeating unit of C. jejuni serotype O:23 and O:36 was synthesized. Coupling of the GlcNPhth-(1${ o}$3)-Gal disaccharide donor with allyl 6-deoxy-altroHep acceptor in the presence of iodonium dicollidine perchlorate (IDCP) promoter afforded the ${alpha}$-galactosidic trisaccharide with high stereoselectivities. Subsequent deacetalation, dephthaloylation, N-acetylation, and hydrogenolytic debenzylation furnished the title compound.

키워드

Altroheptose Trisaccharide Campylobacter jejuni Antigenic repeating unit

다운URL