Here, we have described and illustrated a new endemic species of Scutellaria orthocalyx. This species, from Jeju-do, Korea, is clearly distinguished from other species of Scutellaria orthocalyx, especially its close relative, Scutellaria orthocalyx has relatively many leaves further down the stem. The shape of leaves begins linear and becomes lanceolate. Scutellaria orthocalyx can also have long shaped leaves on the upper part. Scutellaria baicalensis by linear, terete, fistulous and long leaves. A index to these species is provided.