Due to the rapid growth of mobile communication services, many studies have been performed on the biological effects of EMF(Electromagnetic field) exposure. However, it is not easy to create the field uniformity in radio frequency. To overcome this difficulty, the electric field and SAR(Specific Absorption Rate) distribution is developed to measure the whole body exposure system. In this paper, we developed the whole body exposure system for in-vivo study utilizing reverberation chamber which has a high possibility of practical use by substituting previous the EMC chamber. The field uniformity in the test area of the designed reverberation chamber was satisfied by the simulation and measurement data. In animal study of the whole body exposure for a mouse, the results of FDTD simulation were compared with those of measurement to confirm SAR under the electromagnetic exposure. We analyze the electric field distribution in the interior of the reverberation chamber and treat these results in statistical manner. In the CDMA frequency band(PCS ＆ Cellular band), an average value of the whole body SAR and local peak value for a experimental mouse were presented for various input power.