In this study, the Mild slope equation is extended to both rapidly varying topography and nonlinear waves, using the Hamiltonian principle. It is shown that this equation is equivalent to the modified mild-slope equation (Kirby and Misra, 1998) for small amplitude wave, and it is the same form with the nonlinear mild-slope equation (Isobe, 1994) for slowly varying bottom topography. Comparing its numerical solutions with the results of some hydraulic experiments, there is good agreement between them.