The out-of-positioned small female drivers are most likely to be injured during airbag deployment due to their stature and proximity to the steering wheel and airbag module. In order to investigate the injury mechanisms, some experimental studies with Hybrid III 5% female dummy and with female cadavers could be found from the open literatures. However, the given information from those experimental studies is quite limited to the standard conditions and might not be enough to estimate the airbag inflation aggressiveness regarding on the occupant responses and injury. In this study, a finite element analysis has been performed in order to investigate the airbag-induced injuries. A finite element 5% female human model in anatomical details has been developed. The validation results of the model are also introduced in this paper.