Grinding is a finishing operation of products in various areas. Surface roughness of industrial components obtained in grinding operation is a critical quality measure but is a function of many operating parameters and their interactions. To achieve higher surface roughness and to identify the influence of grinding parameters on surface roughness, it is an ideal situation fer using the design of experiments. This paper presents an successful optimization of grinding conditions and prediction of surface roughness using the design of experiments. From the experimental verification tests, it was observed that this approach was useful as a robust design methodology for grinding operation.