Automatic detection of laryngeal diseases by voice is attractive because of its non-intrusive nature. Cepstrum based approach to detect laryngeal cancer shows reliable performance even when the periodicity of voice signals is severely lost, but it has a drawback that it is not robust to channel mismatch due to different microphone characteristics. In this paper, to deal with mismatched training and test microphone conditions, we investigate channel compensation techniques such as Cepstral Mean Subtraction (CMS) and Pole Filtered CMS (PFCMS). According to our experiments, PFCMS yields better performance than CMS. By using PFCMS, we obtained 12% and 40% error reduction over baseline and CMS, respectively.