Objectives: To describe the rate of injuries among infants and toddlers. and to investigate the attitude. knowledge. and practice on safety of their mothers. Methods: The total sample consisted of 308 mothers with infants or toddlers from two public health centers in two cities in Kyunggi Province. A questionnaire was used to collect data. which was analyzed with SPSS 11.5 Win program. Results: Thirty-eight percent of the subjects had experienced home accidents. Fall. burn. and laceration were the most frequently occurred home injuries. Most of the mothers were anxious for child accidents, and $59.4\%$ of mothers thought of safety as a primary concern. The mean score of knowledge on safety was 7.63. and the mean score of practice on safety was 34.76. Safety knowledge was significantly higher in mothers with higher education. higher income. and experience of having information on safety. but safety practice was not different depending on these factors. There was a negative correlation between safety practice and child rearing burden. Conclusions: The rate of injuries among infants and toddlers was still high compared to other developed countries. This study provided basic data about the accidents of infants and toddlers. and the level of safety knowledge and safety practice of their mothers. The related factors found in this study should be considered when providing anticipatory guidance or developing injury prevention programs for mothers.