This study was performed to investigate the perceptions of the opinion leaders, such as government officials, researchers, NGO workers, and journalists on the risks of endocrine disrupters (EDs) and genetically modified organisms (GMOs) as well as the related policies on these two hazards or potential hazards. The opinion leaders generally considered the EDs as the most serious hazard among twenty-one environmental health hazards in Korea, and agreed that the EDs would continuously be the most serious hazard. On overall average, the GMOs were ranked the 11th among the twenty-one health hazards. Further investigation indicated that the GMOs were variously ranked by the group of respondents: they were ranked the 2nd by the NGO workers, the 7th by the journalists, the 9th by the researchers and the 11th by the government officials. In general, the respondents considered the dioxin as a hazard with the highest risk while the GMOs were considered less hazardous. The opinion leaders considered that although the risks of the GMOs and EDs were not fully verified, the risks should be controlled through the legislation. The EDs and GMOs should be separately regulated for the time being, while the EDs should put under more strengthened regulation. It is recommended that a web-site containing the information on the EDs and the GMOs be prepared for the journalists. In addition, a training program in relation to the EDs and the GMOs needs to be organized by the Korean Press Foundation and the Korea Food and Drug Administration to educate the journalists. A committee consisting of government officials, scientists, and NGO workers needs to be established, and it should provide framework of future policies and public relations programs.