Objectives : The purpose of this study is to compare the improvement effects on lumbar spine herniation of nucleus pulpous between neighboring acupuncture points and neighboring-remote acupuncture points by bee venom herbal-acupuncture therapy. Methods : The 30 patients who had a diagnosis of lumbar spine herniation of nucleus pulpous were divided into two groups. Group A was 15 cases treated with bee venom herbal-acupuncture therapy on neighboring acupuncture points, group B was 15 cases treated on neighboring and remote acupuncture points. The two groups were also managed by moxibustion, physical theraphy and herbal medicine. The improvement effects between two groups was estimated by low back pain index and visual analogue scale(VAS) score after 10 days treatment. Results : After 10 days treatment. low back pain index and VAS score were significantly improved in both two groups, but there was no significantly difference between two groups in both low back pain index and VAS score. Conclusion : In this study, there were same effects between neighboring acupuncture points and neighboring-remote acupuncture points bee venom herbal-acupuncture therapy. But further studies are required to confirm the effect of these methods.