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저자명
오명숙,김도림,강지웅,장문석,박선민,고병섭,박성규,Oh. Myung-Sook,Kim. Do-Rim,Kang. Ji-Ung,Chang. Mun-Seog,Park. Sun-Min,Ko. Byoung-Seob,Park. Seong-Ky
간행물명
大韓韓醫學方劑學會誌
권/호정보
2005년|13권 1호|pp.1-7 (7 pages)
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대한한의학방제학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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Objective : Okchun-San(OCS) is known as an effective herbal medicine on Type 2 diabetes. We performed to change OCS formulation for freeze drying capsulation. Methods The mixtures of OCS were extracted with water. finally, the filtered solution were evaporated and lyophilized to dry granules. The various ratio of excipients were studied to determine the formation for capsulizing. The samples were inspected for any difference in color, taste and appearance. Results: The prepared form of OCS were dried and weighted 260kg. The lyophilized dry powder yielding 40kg. The suitable ratio of OCS-dry powder and excipient was 10:1. The average weights of On and placebo capsules were $440{pm}5.28mg$, $465{pm}7.95mg$, respectively. There was no notable change in color and appearance for both capsuled samples throughout the study period. Conclusions: Therefore in can be concluded that freeze drying capsulation is appropriate form of OCS.