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선여택통기탕(仙麗澤通氣湯)이 ovalbumin에 의하여 유발된 allergic mouse의 면역기능에 미치는 영향(影響)
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  • 선여택통기탕(仙麗澤通氣湯)이 ovalbumin에 의하여 유발된 allergic mouse의 면역기능에 미치는 영향(影響)
저자명
고정순,김종한,박수연,최정화,Ko. Jung-Soon,Kim. Jong-Han,Park. Su-Yeon,Choi. Jung-Hwa
간행물명
韓方眼耳鼻咽喉皮膚科學會誌
권/호정보
2005년|18권 1호|pp.94-103 (10 pages)
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대한한방안이비인후피부과학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

Objective: This study was performed to investigate the effects of YTT on allergic bronchial asthma. Methods: The mice were divided into 4 groups induced the allergic bronchial asthma : Three groups(YTT-1, YTT-2, YTT-3) treated YTT and non-treated group(Control). Three oral administration of the herbal solution of YTT were carried out 1 time a day for 2 weeks before antigen sensitization. 2 days later, the mice were sensitized with a subcutaneous injection of ovalbumin(OA) and then 13 days later they were provoked with OA aerosols. Then the cell numbers in bronchoalveolar lavage fluid(BALF), serum level of IgE, WBC, RBC and HGB were measured. Results: 1. On the neutrophil in BALF, groups of YTT-2 and YTT-3 are significantly increased compared with the control group. 2. On the eosinophil in BALF, groups of YTT-1 and YTT-3 are significantly decreased compared with the control group. 3. On the lymphocyte in BALF, YTT-3 group is significantly increased compared with the control group. 4. On the macrophage in BALF, groups of YTT-1 and YTT-3 groups tend to increase. 5. On the serum IgE, groups YTT-1, YTT-2 and YTT-3 are significantly decreased compared with the control group. 6. On WBC in blood, groups of YTT-2, YTT-3 are significant1y decreased compared with the control group. Conclusions: Based on the above results, it is assumed that the oral administration of YTT can help the treatment of allergic bronchial asthma.