In structural design, the design variables are frequently selected from certain discrete values. Various optimization algorithms have been developed fDr discrete design. It is well known that many function evaluations are needed in such optimization. Recently, sequential algorithm with orthogonal arrays (SOA), which is a search algorithm for a local minimum in a discrete space, has been developed. It considerably reduces the number of function evaluations. However, it only finds a local minimum and the final solution depends on the initial values of the design variables. A new algorithm is proposed to adopt a genetic algorithm (GA) in SOA. The GA can find a solution in a global sense. The solution from the GA is used as the initial design of SOA. A sequential usage of the GA and SOA is carried out in an iterative manner until the convergence criteria are satisfied. The performance of the algorithm is evaluated by various examples.