Various kinds of studies for building up U-Korea are now underway. Especially, RFID comes into the spotlight as a core technology of Ubiquitous. Though, the development of higher levels of application is far behind the hardware-based technology in RFID application system. For that reason, In this paper suggests technology using RFID on Ubiquitous and embodies the effective health care application which is one of the application services of user-centered environment It realizes the system which enables us to manage and send data about changing prescriptions and locations of patients effectively under the basis of RFID tag and mobile devices. It also provides the high quality of practical effectiveness of entire system throughout the realization of applications of application server and mobile device. on the basis of framework for providing the various kinds of services and physical elements.