We review here research and development progress achieved in US Plasma Chamber technology roughly over the last decade. In particular, we focus on two major programs carried out in the US: the APEX project (1998-2003) and the US ITER TBM activities (2003-present). The APEX project grew out of the US fusion program emphasis in the late 1990s on more fundamental science and innovation. APEX was commissioned to investigate novel technology concepts for achieving high power density and high temperature reactor coolants. In particular, the idea of liquid walls and the related research is described here, with some detailed examples of liquid metal and molten salt magnetohydrodynamic and free surface effects on flow control and heat transfer. The ongoing US ITER Test Blanket Module (TBM) program is also described, where the current first wall/blanket concepts being considered are the dual coolant lead lithium concept and the solid breeder helium cooled concepts, both using ferritic steel structures. The research described for these concepts includes both thermofluid MHD issues for the liquid metal coolant in the DCLL, and thermomechanical issues for ceramic breeder packed pebble beds in the solid breeder concept. Finally, future directions for ongoing research in these areas are described.