This paper makes a study of a formulation of net filter discrimination(NFD) and its computation for analyzing adjacent channel interference and suggests a systematic algorithm for calculating protection ratios of co-channel and adjacent channel applicable to frequency coordination in the fixed radio relay networks. It is shown that adjacent channel protection ratio can be derived from two factors: One is NFD depending upon receiver filter characteristic as well as transmitter spectrum mask and the other is co-channel protection ratio given by a function of fade margin, modulation scheme, and allowable interference. Actually to show the computing procedure from transmitter spectrum mask and receiver filter characteristic, NFD has been obtained for channel bandwidth of 29.65 and 40 MHz at 6.2 and 6.7 GHz band, respectively. According to the results, NFDs at the first adjacent channel of 29.65 and 40 MHz provide 27.4 and 28.9 dB, respectively. From these data, adjacent channel protection ratios corresponding to each channel bandwidth yield 47.5 and 46.3 dB for a given 64-QAM and 60 km. The proposed method gives some merits of an easy calculation, systematic extension, and applying the same concept to frequency coordination in millimeter radio relay networks.