The purpose of this study is to critically examine conventional spatial measures of individual accessibility, which are based on the notion of spatial proximity, the single reference location, and the unlinked travel model. Using space-time accessibility measures with the travel-activity diary data set of Portland Metro, US, three expectations from spatial measures on spatial patterns of individual accessibility were empirically examined: (1) does individual accessibility decrease with an increase of distance from the CBD?; (2) does the spatial pattern of accessibility resemble that of urban opportunity density pattern?; and (3) are spatial patterns of individual accessibility of different socio- demographic population groups basically similar as people in the same area share the same geographic characteristics regardless of gender, race, age, and so on? First of all, the results showed that spatial variations in individual accessibility were not directly determined by spatial proximity and opportunity density as suggested by previous accessibility measures. The spatial pattern of individual accessibility was dramatically different from that of urban opportunity density High peaks of accessibility level were found far away from the CBD and regional centers. This finding might be associated with the importance of multi-reference locations and linked travels in shaping accessibility in reality. Furthermore, this study found that spatial patterns of accessibility clearly differ between men and women. These findings suggest that access requires more than proximity, and that the interaction between person-specific space-time constraints and the consequential availability of urban opportunities in space-time renders different accessibility experiences to people even in the same region, which would be one of the key ingredients missing from conventional spatial measures of accessibility.