As development of digital technology, many kinds of multimedia data are used variously and requirements for effective use by user are increasing. In order to transfer information fast and precisely what user wants, effective retrieval method is required. As existing multimedia data are impossible to apply the MPEG-1, MPEG-2 and MPEG-4 technologies which are aimed at compression, store and transmission. So MPEG-7 is introduced as a new technology for effective management and retrieval of multimedia data. In this paper, we extract content-based features using color descriptor among the MPEG-7 standardization visual descriptor, and reduce feature data applying PCA(Principal Components Analysis) technique. We model the cerebral cortex and hippocampal neural network in engineering domain, and team content-based feature vectors fast and apply the hippocampal neural network algorithm to compose of optimized feature. And then we present fast and precise retrieval effect when indexing and retrieving.