This paper presents the knowledge and experience we obtained by employing multiprocessor systems as a computer simulation design verification to study high-performance computing system. This paper also describes a case study of symmetric multiprocessors (SMP) kernel on a 32 CPUs CC-NUMA architecture using an actual architecture. A small group of CPUs of CC-NUMA, high-performance computer system, is clustered into a processing node or cluster. By simulating the system design verification tools; we discussed SMP OS kernel on a CC-NUMA multiprocessor architecture performance which is $32\%$ of the total execution time and remote memory access latency is occupied $43\%$ of the OS time. In this paper, we demonstrated our simulation results for multiprocessor, high-performance computing system performance, using simulation-based design verification.