A high-precision centerless grinding machine has been recognized as a core equipment performing the finish outer-diameter grinding process of ferrules which are widely used as fiber optic connectors. In this study, in order to realize the high-precision centerless grinding machine, the structural characteristic analysis and evaluation are carried out on the virtual prototype consisted of the steel bed, hydrostatic GW and RW spindle systems, hydrostatic RW feed mechanism, RW swivel mechanism, and on-machine GW and RW dressers. The loop stiffnesses of centerless grinding machine are estimated based on the relative deformations between GW and RW caused by the grinding forces. And the simulated results illustrate that the concrete-filled bed has the considerable effect on the improvement of the structural stiffness of centerless grinding machine.