- 석창포원지탕(石菖蒲遠志湯)의 Alcoholism에서의 간위(肝胃) 치유 및 학습능력향상 효과
- ㆍ 저자명
- 박영서,임종필,Park. Yeong-Seo,Lim. Jong-Pil
- ㆍ 간행물명
- 동의생리병리학회지
- ㆍ 권/호정보
- 2005년|19권 5호|pp.1292-1295 (4 pages)
- ㆍ 발행정보
- 대한동의생리학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
Effects of the Seokchangpo-Wonji-Tang on recovery from disorder of stomach, liver and mental-faculty in alcoholism were studied using male Sprague-Dawley rats. The rats were assigned into 4 groups; normal, control and Seokchangpo-Wonji-Tang(SWT) group. Control group administered ethanol(25 v/v %) at a dose 3g/kg, while SWT group administered 50mg/kg of SWT 30min before treating same dose of ethanol as control group for 10 days, orally. The gastric ulceration and also GOT and GPT activities in rats were checked, and all groups were subjected to trials of straight channel on the 1st day and to those of multiple T-maze during the following 3 days. The gastric ulceration, GOT and GPT activities were increased in control group, but decreased in SWT group significantly. The time required in normal group for the straight channel of the 2nd and 3rd trials was significantly shorter than that of the 1 st, while the control group showed no significance. In the time required for the multiple T-maze trials, the control group showed no significance. But in the straight or T-maze trials, the SWT group showed significant decrease in the time required against the control group.