This paper investigates that the ambiguity of the boundary between interior space and exterior space in architecture appears universally in history and reveals the various aspects of ambiguous boundary in architecture. The space is formed by the relationship with the surroundings and the boundary of two opposite spaces is apt to be ambiguous according to lots of complex factors. Before Modern Architecture the boundary of interior and exterior space had a tendency to be ambiguous by modifying compositional method of material boundary, that is semi interior-exterior space, the reversion of interior and exterior space and space in space. After Modern Architecture the meaning of physical boundary in space is lost along with dissolution of boundary over the society and the boundary of space comes to be dematerialized by the technology and the change of space perception. The phenomenon of deconstruction in spacial boundary accelerate increasingly according to fluid space, mutually interpenetrated space, visual transparency and adjustment of layers. And contemporary technology is collapsing the meaning itself of space division fundamentally.