The purpose of this paper is to acquire competitiveness faced with a global business so that Korea and China make them put ICT into practice through industrial policy of regional innovation clustering. In the Chapter 2, overall review of industrial spaces theory and the environment in Global-business is conducted. In the Chapter 3, current main economic issue and West Great Development of China are viewed. Chapter 4 proposes models and strategies for the target of regional innovation clustering and phasing in development. The results of this study is that both country should do more long-term cooperation and collecting intensive knowledge for the property of region and preparatory research of regional innovation clustering than do reckless investment.