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반하백출천마탕(半夏白朮天麻湯)이 국소(局所) 뇌허혈(腦虛血)로 인(因)한 치매 병태 백서(白鼠)에 미치는 영향(影響)
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  • 반하백출천마탕(半夏白朮天麻湯)이 국소(局所) 뇌허혈(腦虛血)로 인(因)한 치매 병태 백서(白鼠)에 미치는 영향(影響)
저자명
원호영,최창원,김경수,김경옥,이동원,김수연,Won. Ho-Young,Choi. Chang-Won,Kim. Kyung-Su,Kim. Kyeong-Ok,Lee. Dong-Won,Kim. Su-Youn
간행물명
동의신경정신과학회지
권/호정보
2006년|17권 2호|pp.61-73 (13 pages)
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대한한방신경정신과학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Objective : This study was to investigate the effects of Banhabaekchulchunma-Tang(BCT) on Dementia induced by focal ischemic injury in the rats. Method : Experimental groups were divided into 4 groups ; Normal group, Control group, BCT1 group and BCT2 group. Control group were no treated after focal brain ischemic injury. BCT1 group were administered BCT 0.3 ml/kg to focal brain ischemic injuried rats for 21 days, BCT2 group were administered BCT 1.2 ml/kg to focal brain ischemic injuried rats for 21 days. The present author observed the number of errors on the eight-arm radial maze task , the rate of correct choice on the eight-arm radial maze task, the values of density of Cresyl Violet-stained sections in the hippocampal CA1 and the values of density of Acetlycholin Esterase(AchE) stained nuclei in the hippocampal CA1. Result : 1. The number of errors in the eight-arm radial maze task was significantly decreased in BCT1 group on 1-6th days. And it was significantly decreased in BCT2 group on 1st, 2nd, 3rd and 6th day compared with control group. 2. The rate of correct choice on the eight-arm radial maze task was increased in BCT1 group and BCT2 group compared with control group, but the value was not significant. 3. The values of density of Cresyl Violet-stained sections in the hippocampal CA1 were significantly increased in BCT1 group and BCT2 group compared with control group. 4. The values of density of AchE stained nuclei in the hippocampal CA1 were significantly increased in BCT1 group compared with control group. Conclusion : The present author thought that Banhabaekchulchunma-Tang could be used to cure dementia derived by the phlegm retention of fluid.