Objective : The purpose of this experimental-controlled study was to investigate the characteristics of the autonomic nervous system in students with Keongke by using HRV(Heart rate variability) and PSV(Pupil size variability). Method : The study group was consisted of 11 students with self recognition as the experimental group, and 25 normal students as the control group. Informations on gender and age were obtained by medical charts and personal interviews. By using heart rate variability and pupil size variability, we measured the value of HRT(Heart rate), SDNN(Standard deviation of NN intervals), LFnorm(Low frequency normalization), HFnorm(High frequency normalization), LF/HF ratio, Pupil area, B.S.(Basic size), C.R.(Max Constriction Rate) and 1s.d.(1sec Dilation Rate). I compared the degrees of the sympathetic and parasympathetic activity. Result : 1. In the result of heart rate variability between experimental and control group, none of the parameters of experimental group were significantly different from control group. And even though there were no statistical significance, there were some numerical differences in SDNN, LF norm, HF norm. 2. In pupil size variability, C.R. and 1s.d. of the experimental group were increased compared to control group. Conclusion : The study results suggest that the group with Keongke has differences of autonomic nervous system as compared to those in normal state. Measurement value of PSV is a new technical approach to estimate the autonomic nervous system.