From th Study on A Study on the Thesaurus of Korean medical information for developing search engine, the conclusion is as follow. Knowledge based information system consists of concepts, facts and relation. The final goal of developing the Knowledge based information system is to select, store and control the knowledge and information of Oriental Medicine. Considering limitation of organizing the knowledge system, it is difficult to realize complete basic system and application method. In order to work, it is necessary to combine experts in each part, for example Domain experts, Information and Knowledge engineer. Through the development of knowledge based information system, we can construct EMR(Electronic Medical Record) system in the near future, and it is possible to make semi-expert system. To make Knowledge based information system, we need to establish standards of information that make the distribution of Knowledge and information easily.