Piezoelectric materials produce an electric field by deformation, and deform when subjected to an electric field. The coupling nature of piezoelectric materials has acquired wide applications in electric-mechanical and electric devices, including electric-mechanical actuators, sensors and structures. In this paper, a hollow sphere composed of a radially polarized spherically anisotropic piezoelectric material, e.g., PZT_5 or (Pb) (CoW) $TiO_3$ under internal or external uniform pressure and a constant potential difference between its inner and outer surfaces or combination of these loadings has been studied. Electrodes attached to the inner and outer surfaces of the sphere induce the potential difference. The governing equilibrium equations in radially polarized form are shown to reduce to a coupled system of second-order ordinary differential equations for the radial displacement and electric potential field. These differential equations are solved analytically for seven different sets of boundary conditions. The stress and the electric potential distributions in the sphere are discussed in detail for two piezoceramics, namely PZT _5 and (Pb) (CoW) $TiO_3$. It is shown that the hoop stresses in hollow sphere composed of these materials can be made virtually uniform across the thickness of the sphere by applying an appropriate set of boundary conditions.