Cam mechanisms are one of the most popular devices for generating irregular motion and are widely used in many automatic equipments, such as textile machinery, internal combustion engines and other automatic devices. In order to obtain the positive motion of follower by rotating cam, its shape should be correctly designed and manufactured. In present paper, a CAD/CAM system is developed for shape design of disk cams using relative velocity method and NC code generation using the biarc curve interpolation. And, a disk cam is successfully manufactured by the developed CAD/CAM system. Thus, it is shown that the developed CAD/CAM system can be used for high precision cam profile CNC grinding machine.