Business organizations are trying in various ways to survive and grow up in the rapidly changing environment. A lot of organizations have introduced management innovation skills and attempted to change, but most of them have failed to realize their aims. The reason is that the members of the organization including the chief executive officers did not understand the paradigm of the change management of an organization, and gave weight to the partial efficiency instead of the change management of the organization. In this study, guidelines and principles are suggested to apply the quality management system to the change management of business organizations.