The purpose of this study was to investigate the related factor for the prevalence of musculoskeletal symptoms among 212 sewing worker. The survey was performed with self-administered questionnaire for the risk factors related to musculoskeletal disorders(MSDs) from August 5 to 7 in 2005. The prevalence of musculoskeletal symptoms were 75.8% and the those of the local symptoms were 71.7 % for shoulder, 60.4 % for neck, 35.8 % for arm and 50.9 % for wrist. The risk factors related the self-reported MSDs had not shown in general characteristics. But, there was a significant difference between daily working hour and wrist, working speed and neck, the degree of satisfaction and wrist for work related factor. Also, it was shown the significant difference between chair height and neck, the height of sewing machine and wrist among the space below work station, neck, waist for the prevalence of musculoskeletal symptoms. The significant correlation was shown for daily working hour and wrist, working speed and arm, work load and shoulder and the degree of satisfaction and arm for work related subjective symptom. Considering above results, it is suggested the ergonomic design be provided to working hour, the height of chair and work station as well as daily working hour even there is a significant difference for the prevalence of symptoms in each body part for sewing workers.