Chemical plants should perform Quantitative Risk Assessment that evaluates types of accident, frequency and damage which can happen through using the hazardous equipment and the hazardous materials for preventing and preparing industrial disasters. It is necessary that Chemical plants should include the reliability database which efficiently evaluate the Quantitative Risk Assessment. So in this study, we suggest a which methodology applies Quantitative Risk Assessment on the basis of the constructed data to imply the reliability of industrial facilities and equipment, collection of reliability data, system analysis and development of software.