The connection with combined cross diaphragm is developed for the connection of square CFT column and steel beam and proposed to be used for the frame with asymmetric span length. The structural characteristics of this connection lie in the penetration of the beam flange in the direction of major axis through the column for the smooth flow of stress. The purpose of this study is to analyze the dynamic behavior and stress flow of suggested connection and to evaluate the resistance to shock of connection. Four T-type CFT column-to-beam specimens; two with combined cross diaphragm and the others with interior and through diaphragms, the existing connection types, were made for cyclic load test guided by the load program of ANSI/AISC SSPEC 2002. The results show that the proposed connection is more efficient than existing ones in terms of strength, stress flow and energy absorption and satisfies the seismic performance required in the region of weak/moderate earthquakes.