In an effort to reduce the evaluation time of the precision of manufactured disk cams, an effective measuring method with an exclusively built profile-measuring machine and subsequent data analysis procedure is proposed. The design and measuring data are interpolated by cubic spline curves to compute the precision error which is defined by the maximum and minimum distances between two curves. The minimum zone criterion of ISO is employed to evaluate the form error, and genetic algorithm is used to search the orientation and location of design data for the measured data which minimizes the form error. The proposed system was applied to marine engine cams, and it shows that the form error is reduced to 30% down compared with the method which minimizes the form error with the assumption that the centers of measured data design cam curve are identical.