The aim of this study was to investigate the change of the weight loss, tensile strength, flex stiffness, and color-values of the pigment-dyed cotton, polyester/cotton, polyester and nylon fabrics after washing process. Pigment-dyed cotton and polyester/cotton fabrics were treated with the cellulase, of which concentrations were 0, 1, 3 and 5g/l. The time of washing process ranges from 30 to 120 minutes. Pigment-dyed polyester and nylon fabrics were treated without enzyme, of which the washing temperature were 13, 30, $55^{circ}C$ and the washing time ranges from 30 to 120 minutes. Also, they were tested in terms of the influences of agitation speed(rpm) and additives such as softeners, enzymes, detergents. The weight loss and tensile strength of the pigment-dyed cotton and polyester/cotton fabrics were positively correlated with the concentration of cellulase and washing time. Neither polyester nor nylon fabrics exhibited any change of the weight. All fabrics showed the decline of flex stiffness and decoloration after washing process. Decoloration of cotton and polyester/cotton fabrics was due to both the influence of cellulase and the mechanical rubbing. On the other hand, that of polyester and nylon fabrics was caused by the mechanical rubbing only.