In this paper, autonomous information exchange methodology is studied between IEDs using SOAP protocol based on XML and PtP communication to archive the safety and reliability of large-scale system operation. The SOAP protocol has the advantages in the independency Problem for operating systems, using language, platforms and the security problem because it is XML-based RPC protocol. Inference-based solution of the IED is designed as rule-based solution so that the IED internal status, the system status or the faulted zone can be inferred autonomously using the internal data as well as information data obtained from free information exchange among other IEDS, Also, it is designed so that the inference results and the operation information are transmitted to the above SCADA system, and determined autonomously whether the commands from the SCADA are executed or not. Finally, The inference-based solution of IED and information exchange system among IEDS is implemented using MS Visual C++ MFC, MS SOAP and MS XML. Availability and accuracy of the proposed methodology and the design is verified from diversity simulation reviews for typical distribution substation.