Acne, which intrucdes the pilosebaceous unit, is a chronic inflammatory disease. The symptom of comedones, papules, pustules, cysts, nodules and scar mainly raises on the face, upper back, shoulder and neck. The cause of acne is the secreting growth of sebum, abnormal follicular keratiniziation, the form of group of propionibacterium acnes, and the respones of inflammation etc. But the original mechanism of the cytobiologic level is exactly not known yet. We treated three patients suffered from acne with acupuncture, venesection, Chungsangbangpung-tang, wet dressing with Gamihwangryunhaedok-tang. After treatments we observed the improvement. Based on this study, it is considered that acupuncture, venesection, Chungsangbangpung-tang wet drssing with Gamihwangryunhaedok-tang can be applied to the management of acne.