1. Objectives The purpose of this study is to give an account of the effects of Korean herbal medicine therapy which is based on Sasang constitutional medicine for two patients who were suffering from Yin Exhausted Syndrome. 2. Mothods Patients were diagnosed as having Soyangin Yin Exhausted Syndromes by Physical characteristics, posture, and symptoms and were evaluated with an interview and laboratory test after Sasang constitutional medication. 3. Result After the Sasang constitutional medications of Hyungbangsabek-san(荊防瀉白散), Hyungbangjihwang-tang(荊防地黃湯), Juhryungchajunja-tang(猪笭車前子湯), Shihochungjang-tang(柴胡淸腸湯) were used diarrhea and other symptoms were improved. 4. Conclusions These case studies show an efficient result of using Sasang traditional medicine in the treatment of Yin Exhausted Syndrome.