The COMS(Communication, Ocean & Meteorological Satellite) is the geostationary satellite which will be performing three main objectives such as meteorological service, ocean monitoring and Ka-band satellite communications. In order to accomplish these missions, the COMS system needs to implement a specific electrical/mechanical interface functions which are requested by each payload units. This paper describes a on-board interface hardware design for COMS Meteorological Imager(MI). The Meteorological Imager Interface Unit(MI2U) achieves, through MIL-STD-15533 system bus, the interface between the Spacecraft Computer Unit(SCU) and the instrument which is dedicated to MI. MI2U provides a necessary power input to MI from +50V Power Supply Regulator(PSR), and allows adaptation of the specific payload interfaces and protocol to COMS spacecraft.