Objectives This study observed the efficacy of bee venom pharmacopuncture on the treatment of Molluscum Contagiosum commonly manifesting in children. Methods 104 patients admitted for Molluscum Contagiosum at Love Blossoming Oriental medicine clinic from August 2005 to August 2006 were administered with Bee Venom Pharmacopuncture and measured and analyzed changes in symptoms. Results 1. Regardless of age or duration of Molluscum Contagiosum, all 104 patients showed improvement. 2. Recurrence of Molluscum Contagiosum was not noticeable when treated with Bee Venom Pharmacopuncture, and the duration of treatment was significantly shorter than treating with conventional allopathic ointment. 3. Regardless of size or location of Molluscum Contagiosum, most cases improved with one or two treatments. Conclusion Based on above findings, we can deduce Bee Venom Pharmacopuncture has superior anti-viral effects on the pox virus of molluscum contagiosum (MCV1,2).